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3,4-methylenedioxymethamphetamine (MDMA) is a synthetic drug that alters mood and perception (awareness of surrounding objects and conditions). It is chemically similar to both stimulants and hallucinogens, producing feelings of increased energy, pleasure, emotional warmth, and distorted sensory and time perception.

Pure MDMA. MDMA was initially popular in the nightclub scene and at all-night dance parties (“raves”), but the drug now affects a broader range of people who more commonly call the drug Ecstasy or Molly.
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People who use MDMA usually take it as a capsule or tablet, though some swallow it in liquid form or snort the powder. The popular nickname Molly (slang for “molecular”) often refers to the supposedly “pure” crystalline powder form of MDMA, usually sold in capsules. However, people who purchase powder or capsules sold as Molly often actually get other drugs such as synthetic cathinones.

mdma crystalSome people take MDMA in combination with other drugs such as alcohol or marijuana.
How does MDMA affect the brain?

MDMA increases the activity of three brain chemicals:

Dopamine—causes a surge in euphoria and increased energy/activity
Norepinephrine—increases heart rate and blood pressure, which are particularly risky for people with heart and blood vessel problems
Serotonin—affects mood, appetite, sleep, and other functions. It also triggers hormones that affect sexual arousal and trust. The release of large amounts of serotonin likely causes the emotional closeness, elevated mood, and empathy felt by those who use MDMA.

Other health effects include:

nausea
muscle cramping
involuntary teeth clenching
blurred vision
chills
sweating
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Magic mushrooms are the commonest compound people use these days as being a microdose. They’re straightforward to just take and there’s plenty of investigate on the specific Rewards and protection of working with this compound [4].

Dopamine. This brain chemical is associated with improved Electrical power and activating the reward method, which can cause the pleasurable reinforcement of continued use with the drug.

Reports exhibit some of these drugs even contain rat poison. Buyers will usually consider An additional dose when they truly feel as if they are beginning to arrive down from the drug.

Better still, the experiences in the observe can truly feel fairly one of a kind and effective due to the choice of substances chosen for it.

At the first signs of drug use or abuse, it’s very important to intervene. Recovery can be done, with the right Experienced means. Find out more about treatment options and how you or even a liked just one might get the assistance you would like.

Leisure usage of MDMA ongoing Even so and remains widespread among the customers of nightlife scenes, festival attendees, together with other communities.

Just after Molly has still left a person’s method, a “crash” is frequent. This crash involves feelings of despair and psychological withdrawal resulting from neurotransmitter depletion.

Mescaline is especially grounding and has a powerful tendency for producing men and women experience a lot more current and “in the moment” than many of the other psychedelics.

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Norepinephrine. This brain chemical increases coronary heart price and hypertension, and will get more info Enjoy a hand in a lot of the heightened physiological responses to ecstasy use.

There’s loads of debate no matter if it’s Risk-free to microdose MDMA or not. This compound has an affinity for a particular form of serotonin receptor known as the five-HT2B receptor — which is found in substantial concentrations in the guts. It’s believed that activating this receptor way too commonly could lead on to coronary heart valve disorders.

Ecstasy gets sold as tablets, with enjoyment logos printed on them. This makes them more pleasing and straightforward to eat in a party ecosystem.

: Persistent use of MDMA could possibly be associated with the development of Actual physical dependence (the development of both tolerance and withdrawal syndromes); on the other hand, the research is mixed concerning this. There is not any formal identified withdrawal syndrome linked to Continual use of MDMA, even though it is normally identified that tolerance to MDMA does produce.